Anti-MYDGF antibody (STJA0007501)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human MYDGF
General Information
| Short Description | Rabbit polyclonal anti-Myeloid-derived growth factor for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MYDGF |
| Gene ID | 56005 |
| Uniprot ID | MYDGF_HUMAN |
| Immunogen | Synthesized peptide derived from human MYDGF |
| Specificity | This antibody detects endogenous levels of MYDGF at Human, Mouse |
Additional Info
| Function | Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. Involved in endothelial cell proliferation and angiogenesis. |
| Protein Name | Myeloid-Derived Growth FactorMydgf |
| Database Links | Reactome: R-HSA-381038 |
| Cellular Localisation | SecretedEndoplasmic Reticulum-Golgi Intermediate CompartmentEndoplasmic ReticulumGolgi ApparatusThe C-Terminal Rtel Motif May Provide Retention In The Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-Myeloid-Derived Growth Factor antibodyAnti-Mydgf antibodyAnti-MYDGF antibodyAnti-C19orf10 antibody |
Information sourced from Uniprot.org