Anti-MYCNOS antibody (2-52 aa) (STJ196516)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human MYCNOS at the amino acid range 2-52
General Information
| Short Description | Rabbit polyclonal anti-N-cym protein (2-52 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:5000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MYCNOSUniprot ID=NCYM_HUMAN" |
| Immunogen | Synthesized peptide derived from the human MYCNOS at the amino acid range 2-52 |
| Immunogen Region | 2-52 aa |
| Specificity | This antibody detects endogenous levels of human MYCNOS |
Additional Info
| Function | Regulates stability of MYCN in neuroblastoma cells by inhibiting GSK3B-mediated MYCN phosphorylation. Inhibits GSK3B activity by promoting its phosphorylation at 'Ser-9'. |
| Protein Name | N-Cym ProteinN-Myc Opposite Strand |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-N-Cym Protein antibodyAnti-N-Myc Opposite Strand antibodyAnti-MYCNOS antibodyAnti-CYMN antibodyAnti-NCYM antibody |
Information sourced from Uniprot.org