Anti-MYBL1 antibody (231-280 aa) (STJ91589)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human MYB-A at the amino acid range 231-280
General Information
| Short Description | Rabbit polyclonal anti-Myb-related protein A (231-280 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MYBL1 |
| Gene ID | 4603 |
| Uniprot ID | MYBA_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human MYB-A at the amino acid range 231-280 |
| Immunogen Region | 231-280 aa |
| Specificity | A-Myb Polyclonal Antibody detects endogenous levels of A-Myb protein. |
Additional Info
| Function | Transcription factor that specifically recognizes the sequence 5'-YAACGTG-3'. Acts as a master regulator of male meiosis by promoting expression of piRNAs: activates expression of both piRNA precursor RNAs and expression of protein-coding genes involved in piRNA metabolism. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity. Transcriptional activator of SOX30. |
| Protein Name | Myb-Related Protein AA-MybMyb-Like Protein 1 |
| Database Links | Reactome: R-HSA-5601884 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Myb-Related Protein A antibodyAnti-A-Myb antibodyAnti-Myb-Like Protein 1 antibodyAnti-MYBL1 antibodyAnti-AMYB antibody |
Information sourced from Uniprot.org