Anti-MYBBP1A antibody (STJA0007600)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human MYBBP1A
General Information
| Short Description | Rabbit polyclonal anti-Myb-binding protein 1A for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MYBBP1A |
| Gene ID | 10514 |
| Uniprot ID | MBB1A_HUMAN |
| Immunogen | Synthesized peptide derived from human MYBBP1A |
| Specificity | This antibody detects endogenous levels of MYBBP1A at Human, Mouse, Rat |
Additional Info
| Function | May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2. Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter. Has a role in rRNA biogenesis together with PWP1. |
| Protein Name | Myb-Binding Protein 1a |
| Database Links | Reactome: R-HSA-5250924 |
| Cellular Localisation | CytoplasmNucleusNucleolusShuttles Between The Nucleus And CytoplasmNuclear Import May Be Mediated By Kpna2While Export Appears To Depend Partially On Xpo1/Crm1Predominantly Nucleolar |
| Alternative Antibody Names | Anti-Myb-Binding Protein 1a antibodyAnti-MYBBP1A antibodyAnti-P160 antibody |
Information sourced from Uniprot.org