Anti-MXI1 antibody (76-295) (STJ28744)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MXI1 (76-295) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MXI1 |
| Gene ID | 4601 |
| Uniprot ID | MXI1_HUMAN |
| Immunogen Region | 76-295 |
| Immunogen Sequence | LLEAASYLEQIEKENKKCEH GYASSFPSMPSPRLQHSKPP RRLSRAQKHSSGSSNTSTAN RSTHNELEKNRRAHLRLCLE RLKVLIPLGPDCTRHTTLGL LNKAKAHIKKLEEAERKSQH QLENLEREQRFLKWRLEQLQ GPQEMERIRMDSIGSTISSD RSDSEREEIEVDVESTEFSH GEVDNISTTSISDIDDHSSL PSIGSDEGYSSASVKLSFTS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 76-295 of human MXI1 (NP_569157.2). |
Additional Info
| Tissue Specificity | High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle. |
| Function | Transcriptional repressor. MXI1 binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CACGATG-3'. MXI1 thus antagonizes MYC transcriptional activity by competing for MAX. |
| Protein Name | Max-Interacting Protein 1Max Interactor 1Class C Basic Helix-Loop-Helix Protein 11Bhlhc11 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Max-Interacting Protein 1 antibodyAnti-Max Interactor 1 antibodyAnti-Class C Basic Helix-Loop-Helix Protein 11 antibodyAnti-Bhlhc11 antibodyAnti-MXI1 antibodyAnti-BHLHC11 antibody |
Information sourced from Uniprot.org