Anti-MXD1 antibody (STJA0007161)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human MXD1
General Information
| Short Description | Rabbit polyclonal anti-Max dimerization protein 1 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MXD1 |
| Gene ID | 4084 |
| Uniprot ID | MAD1_HUMAN |
| Immunogen | Synthesized peptide derived from human MXD1 |
| Specificity | This antibody detects endogenous levels of MXD1 at Human |
Additional Info
| Function | Component of a transcriptional repressor complex together with MAX. In complex with MAX binds to the core DNA sequence 5'-CACGATG-3'. Antagonizes MYC transcriptional activity by competing with MYC for MAX binding. Binds to the TERT promoter and represses telomerase expression, possibly by interfering with MYC binding. |
| Protein Name | Max Dimerization Protein 1Max Dimerizer 1Protein Mad |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Max Dimerization Protein 1 antibodyAnti-Max Dimerizer 1 antibodyAnti-Protein Mad antibodyAnti-MXD1 antibodyAnti-MAD antibody |
Information sourced from Uniprot.org