| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Interferon-induced GTP-binding protein Mx2 (Internal) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC-p 1:50-300 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MX2 |
| Gene ID: |
4600 |
| Uniprot ID: |
MX2_HUMAN |
| Immunogen Region: |
Internal |
| Specificity: |
MxB Polyclonal Antibody detects endogenous levels of MxB protein. |
| Immunogen: |
Synthesized peptide derived from the Internal region of human MxB. |
| Function | Interferon-induced dynamin-like GTPase with potent antiviral activity against human immunodeficiency virus type 1 (HIV-1). Acts by targeting the viral capsid and affects the nuclear uptake and/or stability of the HIV-1 replication complex and the subsequent chromosomal integration of the proviral DNA. Exhibits antiviral activity also against simian immunodeficiency virus (SIV-mnd). May play a role in regulating nucleocytoplasmic transport and cell-cycle progression. |
| Protein Name | Interferon-Induced Gtp-Binding Protein Mx2Interferon-Regulated Resistance Gtp-Binding Protein MxbMyxovirus Resistance Protein 2P78-Related Protein |
| Database Links | Reactome: R-HSA-1169408Reactome: R-HSA-909733 |
| Cellular Localisation | CytoplasmNucleusNuclear Pore ComplexLocalization To Nuclear Pores Requires Gtp-Binding |
| Alternative Antibody Names | Anti-Interferon-Induced Gtp-Binding Protein Mx2 antibodyAnti-Interferon-Regulated Resistance Gtp-Binding Protein Mxb antibodyAnti-Myxovirus Resistance Protein 2 antibodyAnti-P78-Related Protein antibodyAnti-MX2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
