• Western blot analysis of extracts of various cell lines, using MVK antibody (STJ27307) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Anti-MVK antibody (40-300) (STJ27307)

SKU:
STJ27307

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MVK (40-300) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MVK
Gene ID: 4598
Uniprot ID: KIME_HUMAN
Immunogen Region: 40-300
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human MVK (NP_000422.1).
Immunogen Sequence: RLQPHSNGKVDLSLPNIGIK RAWDVARLQSLDTSFLEQGD VTTPTSEQVEKLKEVAGLPD DCAVTERLAVLAFLYLYLSI CRKQRALPSLDIVVWSELPP GAGLGSSAAYSVCLAAALLT VCEEIPNPLKDGDCVNRWTK EDLELINKWAFQGERMIHGN PSGVDNAVSTWGGALRYHQG KISSLKRSPALQILLTNTKV PRNTRALVAGVRNRLLKFPE IVAPLLTSIDAISLECERV
Function Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis.
Protein Name Mevalonate Kinase
Mk
Database Links Reactome: R-HSA-191273
Reactome: R-HSA-2426168
Cellular Localisation Cytoplasm
Peroxisome
Alternative Antibody Names Anti-Mevalonate Kinase antibody
Anti-Mk antibody
Anti-MVK antibody

Information sourced from Uniprot.org

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