Anti-MUTYH antibody (1-265) (STJ11103855)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Adenine Dna Glycosylase (1-265) antibody for use in IHC-P, IF, ICC and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MUTYH |
| Gene ID | 4595 |
| Uniprot ID | MUTYH_HUMAN |
| Immunogen Region | 1-265 |
| Immunogen Sequence | MTPLVSRLSRLWAIMRKPRA AVGSGHRKQAASQEGRQKHA KNNSQAKPSACDGLARQPEE VVLQASVSSYHLFRDVAEVT AFRGSLLSWYDQEKRDLPWR RRAEDEMDLDRRAYAVWVSE VMLQQTQVATVINYYTGWMQ KWPTLQDLASASLEEVNQLW AGLGYYSRGRRLQEGARKVV EELGGHMPRTAETLQQLLPG VGRYTAGAIASIAFGQATGV VDGNVARVLCRVRAIGADP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-265 of human MUTYH (NP_001041636.1). |
Additional Info
| Function | Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities. |
| Protein Name | Adenine Dna GlycosylaseMuty HomologHmyh |
| Database Links | Reactome: R-HSA-110330Reactome: R-HSA-110331Reactome: R-HSA-110357Reactome: R-HSA-9608287 Q9UIF7-3Reactome: R-HSA-9608290 |
| Cellular Localisation | NucleusMitochondrion |
| Alternative Antibody Names | Anti-Adenine Dna Glycosylase antibodyAnti-Muty Homolog antibodyAnti-Hmyh antibodyAnti-MUTYH antibodyAnti-MYH antibody |
Information sourced from Uniprot.org