Anti-Musashi-2 antibody (200-300) [S4MR] (STJ11103154)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Musashi-2 (MSI2) (200-300) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S4MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MSI2 |
| Gene ID | 124540 |
| Uniprot ID | MSI2H_HUMAN |
| Immunogen Region | 200-300 |
| Immunogen Sequence | ARGLPYTMDAFMLGMGMLGY PNFVATYGRGYPGFAPSYGY QFPGFPAAAYGPVAAAAVAA ARGSGSNPARPGGFPGANSP GPVADLYGPASQDSGVGNYI S |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Musashi-2 (MSI2) (Q96DH6). |
Additional Info
| Tissue Specificity | Ubiquitous.detected at low levels. |
| Post Translational Modifications | Phosphorylated. Ubiquitinated by the RHOBTB2-CUL3-RBX1 ubiquitin ligase complex. |
| Function | RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system. |
| Protein Name | Rna-Binding Protein Musashi Homolog 2Musashi-2 |
| Database Links | Reactome: R-HSA-9013418 |
| Cellular Localisation | CytoplasmAssociated With Polysomes |
| Alternative Antibody Names | Anti-Rna-Binding Protein Musashi Homolog 2 antibodyAnti-Musashi-2 antibodyAnti-MSI2 antibody |
Information sourced from Uniprot.org