Anti-MUPCDH antibody (C-Term) (STJ71484)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-MUPCDH (C-Term) is suitable for use in ELISA research applications. |
| Applications | Pep-ELISA |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Preliminary experiments in Human Colon, Ileum and Kidney lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). We would appreciate any feedback fr |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | CDHR5 |
| Gene ID | 53841 |
| Uniprot ID | CDHR5_HUMAN |
| Accession Number | NP_068743.2; NP_112554.2 |
| Immunogen Region | C-Term |
| Immunogen Sequence | PYDAPGGDDSY |
| Specificity | This antibody is expected to recognise both reported isoforms (NP_068743.2; NP_112554.2). |
Additional Info
| Post Translational Modifications | N- and O-glycosylated. |
| Function | Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR2 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation. |
| Protein Name | Cadherin-Related Family Member 5Mu-ProtocadherinMucin And Cadherin-Like ProteinMucin-Like ProtocadherinMlpcdh |
| Cellular Localisation | Apical Cell MembraneSingle-Pass Type I Membrane ProteinCell ProjectionMicrovillus Membrane |
| Alternative Antibody Names | Anti-Cadherin-Related Family Member 5 antibodyAnti-Mu-Protocadherin antibodyAnti-Mucin And Cadherin-Like Protein antibodyAnti-Mucin-Like Protocadherin antibodyAnti-Mlpcdh antibodyAnti-CDHR5 antibodyAnti-MUCDHL antibodyAnti-MUPCDH antibodyAnti-UNQ2781 antibodyAnti-PRO7168 antibody |
Information sourced from Uniprot.org