| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Pig |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-MUNC18C (514-527) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 60kDa band observed in Human Platelets lysates (calculated MW of 67.8kDa according to NP_009200.2). Recommended concentration: 0.1-0.3µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | STXBP3 |
| Gene ID: | 6814 |
| Uniprot ID: | STXB3_HUMAN |
| Immunogen Region: | 514-527 |
| Accession Number: | NP_009200.2 |
| Immunogen Sequence: | RQKPRANYLEDRKN |
| Post Translational Modifications | Phosphorylated by PKC in platelets in response to thrombin stimulation.phosphorylation inhibits binding to STX4. |
| Function | Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes. |
| Protein Name | Syntaxin-Binding Protein 3Platelet Sec1 ProteinPspProtein Unc-18 Homolog 3Unc18-3Protein Unc-18 Homolog CUnc-18c |
| Database Links | Reactome: R-HSA-114516Reactome: R-HSA-1445148 |
| Cellular Localisation | CytoplasmCytosolCell MembraneIn PlateletsPredominantly CytosolicLow Amounts Membrane-Associated |
| Alternative Antibody Names | Anti-Syntaxin-Binding Protein 3 antibodyAnti-Platelet Sec1 Protein antibodyAnti-Psp antibodyAnti-Protein Unc-18 Homolog 3 antibodyAnti-Unc18-3 antibodyAnti-Protein Unc-18 Homolog C antibodyAnti-Unc-18c antibodyAnti-STXBP3 antibody |
Information sourced from Uniprot.org
