Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).

Anti-MUC5B antibody (1810-1890 aa) (STJ190985)

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STJ190985
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Short Description :Rabbit polyclonal anti-Mucin-5B (1810-1890 aa) for use in IHC and IF in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC/IF
Host:Rabbit
Reactivity:Human/Rat/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:IHC-P 1:50-300
IF 1:50-200
Formulation:Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:MUC5B
Gene ID:727897
Uniprot ID:MUC5B_HUMAN
Immunogen:Synthesized peptide derived from the human protein at the amino acid range 1810-1890
Immunogen Region:1810-1890 aa
Specificity:MUC5B Polyclonal Antibody detects endogenous levels of protein.
Post Translational Modifications Highly glycosylated. C-, N- and O-glycosylated. C-mannosylated in the Cys-rich subdomains probably on the first Trp residue of the WXXW motif. Highly O-glycosylated in the Ser/Thr-rich tandem repeat (TR) region. The repeat region is about 59% O-glycosylated with a high abundance of NeuAc(2)Hex(1)HexNac1-ol.
Function Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus.
Protein Name Mucin-5b
Muc-5b
Cervical Mucin
High Molecular Weight Salivary Mucin Mg1
Mucin-5 Subtype B - Tracheobronchial
Sublingual Gland Mucin
Database Links Reactome: R-HSA-5083625
Reactome: R-HSA-5083632
Reactome: R-HSA-5083636
Reactome: R-HSA-5621480
Reactome: R-HSA-913709
Reactome: R-HSA-977068
Cellular Localisation Secreted
Alternative Antibody Names Anti-Mucin-5b antibody
Anti-Muc-5b antibody
Anti-Cervical Mucin antibody
Anti-High Molecular Weight Salivary Mucin Mg1 antibody
Anti-Mucin-5 Subtype B - Tracheobronchial antibody
Anti-Sublingual Gland Mucin antibody
Anti-MUC5B antibody
Anti-MUC5 antibody

Information sourced from Uniprot.org

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