Anti-MUC13 antibody (STJA0038002)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human MUC13
General Information
| Short Description | Rabbit monoclonal anti-MUC13 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | IHC 1:100-1:200 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | MUC13 |
| Gene ID | 56667 |
| Uniprot ID | MUC13_HUMAN |
| Immunogen | A synthesized peptide derived from human MUC13 |
Additional Info
| Tissue Specificity | Highly expressed in epithelial tissues, particularly those of the gastrointestinal and respiratory tracts, such as large intestine and trachea, followed by kidney, small intestine, appendix and stomach. |
| Post Translational Modifications | Cleaved into two subunits, alpha and beta, probably between the first EGF domain and the SEA domain. Beta subunit contains the cytoplasmic tail and alpha subunit the extracellular tail. The homooligomerization into dimers is dependent on intrachain disulfide bonds. Highly N-glycosylated. |
| Function | Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. |
| Protein Name | Mucin-13Muc-13Down-Regulated In Colon Cancer 1 |
| Database Links | Reactome: R-HSA-5083625Reactome: R-HSA-5083632Reactome: R-HSA-5083636Reactome: R-HSA-5621480Reactome: R-HSA-913709Reactome: R-HSA-9696264Reactome: R-HSA-9696270Reactome: R-HSA-9696273Reactome: R-HSA-977068 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinApical Cell MembraneSecretedAlso Exists As A Soluble Form |
| Alternative Antibody Names | Anti-Mucin-13 antibodyAnti-Muc-13 antibodyAnti-Down-Regulated In Colon Cancer 1 antibodyAnti-MUC13 antibodyAnti-DRCC1 antibodyAnti-RECC antibodyAnti-UNQ6194 antibodyAnti-PRO20221 antibody |
Information sourced from Uniprot.org