Anti-MTUS1 antibody (STJA0007474)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human MTUS1
General Information
| Short Description | Rabbit polyclonal anti-Microtubule-associated tumor suppressor 1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MTUS1 |
| Gene ID | 57509 |
| Uniprot ID | MTUS1_HUMAN |
| Immunogen | Synthesized peptide derived from human MTUS1 |
| Specificity | This antibody detects endogenous levels of MTUS1 at Human, Mouse, Rat |
Additional Info
| Function | Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth. |
| Protein Name | Microtubule-Associated Tumor Suppressor 1At2 Receptor-Binding ProteinAngiotensin-Ii Type 2 Receptor-Interacting ProteinMitochondrial Tumor Suppressor 1 |
| Database Links | |
| Cellular Localisation | MitochondrionGolgi ApparatusCell MembraneNucleusIn NeuronsTranslocates Into The Nucleus After Treatment With Angiotensin-IiIsoform 1: CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCytoplasmSpindleLocalizes With The Mitotic Spindle During Mitosis And With The Intercellular Bridge During Cytokinesis |
| Alternative Antibody Names | Anti-Microtubule-Associated Tumor Suppressor 1 antibodyAnti-At2 Receptor-Binding Protein antibodyAnti-Angiotensin-Ii Type 2 Receptor-Interacting Protein antibodyAnti-Mitochondrial Tumor Suppressor 1 antibodyAnti-MTUS1 antibodyAnti-ATBP antibodyAnti-ATIP antibodyAnti-GK1 antibodyAnti-KIAA1288 antibodyAnti-MTSG1 antibody |
Information sourced from Uniprot.org