Anti-MTRFR antibody (STJA0008435)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human C12orf65
General Information
| Short Description | Rabbit polyclonal anti-Mitochondrial translation release factor in rescue for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MTRFR |
| Gene ID | 91574 |
| Uniprot ID | MTRFR_HUMAN |
| Immunogen | Synthesized peptide derived from human C12orf65 |
| Specificity | This antibody detects endogenous levels of C12orf65 at Human, Mouse |
Additional Info
| Post Translational Modifications | Methylation of glutamine in the GGQ triplet by HEMK1. |
| Function | Part of a mitoribosome-associated quality control pathway that prevents aberrant translation by responding to interruptions during elongation. As heterodimer with MTRES1, ejects the unfinished nascent chain and peptidyl transfer RNA (tRNA), respectively, from stalled ribosomes. Recruitment of mitoribosome biogenesis factors to these quality control intermediates suggests additional roles for MTRES1 and MTRF during mitoribosome rescue. |
| Protein Name | Mitochondrial Translation Release Factor In Rescue |
| Database Links | |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Mitochondrial Translation Release Factor In Rescue antibodyAnti-MTRFR antibodyAnti-C12orf65 antibodyAnti-My030 antibody |
Information sourced from Uniprot.org