| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Mitochondrial translation release factor in rescue is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MTRFR |
| Gene ID: |
91574 |
| Uniprot ID: |
MTRFR_HUMAN |
| Specificity: |
This antibody detects endogenous levels of C12orf65 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human C12orf65 |
| Post Translational Modifications | Methylation of glutamine in the GGQ triplet by HEMK1. |
| Function | Part of a mitoribosome-associated quality control pathway that prevents aberrant translation by responding to interruptions during elongation. As heterodimer with MTRES1, ejects the unfinished nascent chain and peptidyl transfer RNA (tRNA), respectively, from stalled ribosomes. Recruitment of mitoribosome biogenesis factors to these quality control intermediates suggests additional roles for MTRES1 and MTRF during mitoribosome rescue. |
| Protein Name | Mitochondrial Translation Release Factor In Rescue |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Mitochondrial Translation Release Factor In Rescue antibodyAnti-MTRFR antibodyAnti-C12orf65 antibodyAnti-My030 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
