Anti-MTPAP antibody (445-495 aa) (STJ194598)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human PAPD1 at the amino acid range 445-495
General Information
| Short Description | Rabbit polyclonal anti-PolyA RNA polymerase, mitochondrial (445-495 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MTPAP |
| Gene ID | 55149 |
| Uniprot ID | PAPD1_HUMAN |
| Immunogen | Synthesized peptide derived from the human PAPD1 at the amino acid range 445-495 |
| Immunogen Region | 445-495 aa |
| Specificity | This antibody detects endogenous levels of PAPD1 at Human/Mouse |
Additional Info
| Function | Polymerase that creates the 3' poly(A) tail of mitochondrial transcripts. Can use all four nucleotides, but has higher activity with ATP and UTP (in vitro). Plays a role in replication-dependent histone mRNA degradation. May be involved in the terminal uridylation of mature histone mRNAs before their degradation is initiated. Might be responsible for the creation of some UAA stop codons which are not encoded in mtDNA. |
| Protein Name | Poly(A Rna Polymerase - MitochondrialPapPap-Associated Domain-Containing Protein 1Polynucleotide AdenylyltransferaseTerminal Uridylyltransferase 1Tutase 1Mtpap |
| Database Links | |
| Cellular Localisation | CytoplasmMitochondrion |
| Alternative Antibody Names | Anti-Poly(A Rna Polymerase - Mitochondrial antibodyAnti-Pap antibodyAnti-Pap-Associated Domain-Containing Protein 1 antibodyAnti-Polynucleotide Adenylyltransferase antibodyAnti-Terminal Uridylyltransferase 1 antibodyAnti-Tutase 1 antibodyAnti-Mtpap antibodyAnti-MTPAP antibodyAnti-PAPD1 antibody |
Information sourced from Uniprot.org