• Immunohistochemistry analysis of MTNR1A in paraffin-embedded Mouse brain using MTNR1A Rabbit polyclonal antibody (STJ114997) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of MTNR1A in paraffin-embedded Rat brain using MTNR1A Rabbit polyclonal antibody (STJ114997) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of lysates from Mouse eye, using MTNR1A Rabbit polyclonal antibody (STJ114997) at 1:2000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Anti-MTNR1A antibody (281-350) (STJ114997)

SKU:
STJ114997

£169.50 - £449.50
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MTNR1A (281-350) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:5000
IHC-P 1:100-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MTNR1A
Gene ID: 4543
Uniprot ID: MTR1A_HUMAN
Immunogen Region: 281-350
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 281-350 of human MTNR1A (NP_005949.1).
Immunogen Sequence: YYMAYFNSCLNAIIYGLLNQ NFRKEYRRIIVSLCTARVFF VDSSNDVADRVKWKPSPLMT NNNVVKVDSV
Tissue Specificity Expressed in hypophyseal pars tuberalis and hypothalamic suprachiasmatic nuclei (SCN). Hippocampus.
Function High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
Protein Name Melatonin Receptor Type 1a
Mel-1a-R
Mel1a Receptor
Database Links Reactome: R-HSA-373076
Reactome: R-HSA-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Melatonin Receptor Type 1a antibody
Anti-Mel-1a-R antibody
Anti-Mel1a Receptor antibody
Anti-MTNR1A antibody

Information sourced from Uniprot.org

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