Anti-MTMR2 antibody (STJA0009571)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human MTMR2
General Information
| Short Description | Rabbit polyclonal anti-Myotubularin-related protein 2 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MTMR2 |
| Gene ID | 8898 |
| Uniprot ID | MTMR2_HUMAN |
| Immunogen | Synthesized peptide derived from human MTMR2 |
| Specificity | This antibody detects endogenous levels of MTMR2 at Human, Mouse |
Additional Info
| Function | Lipid phosphatase that specifically dephosphorylates the D-3 position of phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate, generating phosphatidylinositol and phosphatidylinositol 5-phosphate. Regulates the level of these phosphoinositides critical for various biological processes including autophagy initiation and autophagosome maturation. |
| Protein Name | Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase Mtmr2Myotubularin-Related Protein 2Phosphatidylinositol-3-Phosphate Phosphatase |
| Database Links | Reactome: R-HSA-1483248Reactome: R-HSA-1660499Reactome: R-HSA-1660516Reactome: R-HSA-1660517 |
| Cellular Localisation | CytoplasmEarly Endosome MembranePeripheral Membrane ProteinPerinuclear RegionCell ProjectionAxonEndosome MembranePartly Associated With MembranesLocalizes To Vacuoles In Hypo-Osmotic Conditions |
| Alternative Antibody Names | Anti-Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase Mtmr2 antibodyAnti-Myotubularin-Related Protein 2 antibodyAnti-Phosphatidylinositol-3-Phosphate Phosphatase antibodyAnti-MTMR2 antibodyAnti-KIAA1073 antibody |
Information sourced from Uniprot.org