| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MTMR14 |
| Gene ID: | 64419 |
| Uniprot ID: | MTMRE_HUMAN |
| Immunogen Region: | 335-500 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 335-500 of human MTMR14 (NP_001070993.1). |
| Immunogen Sequence: | DRTPLFISLLRLSLWADGLI HTSLKPTEILYLTVAYDWFL FGHMLVDRLSKGEEIFFFCF NFLKHITSEEFSALKTQRRK SLPARDGGFTLEDICMLRRK DRGSTTSLGSDFSLVMESSP GATGSFTYEAVELVPAGAPT QAAWRKSHSSSPQSVLWNRP QPSEDR |
| Tissue Specificity | Expressed in various tissues, including heart, skeletal muscle, placenta, liver, lung, kidney and pancreas. |
| Function | Lipid phosphatase that specifically dephosphorylates the D-3 position of phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate, generating phosphatidylinositol and phosphatidylinositol 5-phosphate. |
| Protein Name | Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase Mtmr14 Hcv Ns5a-Transactivated Protein 4 Splice Variant A-Binding Protein 1 Ns5atp4abp1 Myotubularin-Related Protein 14 Phosphatidylinositol-3-Phosphate Phosphatase Hjumpy |
| Database Links | Reactome: R-HSA-1632852 Reactome: R-HSA-1660499 |
| Cellular Localisation | Cytoplasm Found In Reticular Structures And Plasma Membrane Ruffles Concentrated Near The Nucleus |
| Alternative Antibody Names | Anti-Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase Mtmr14 antibody Anti-Hcv Ns5a-Transactivated Protein 4 Splice Variant A-Binding Protein 1 antibody Anti-Ns5atp4abp1 antibody Anti-Myotubularin-Related Protein 14 antibody Anti-Phosphatidylinositol-3-Phosphate Phosphatase antibody Anti-Hjumpy antibody Anti-MTMR14 antibody Anti-C3orf29 antibody |
Information sourced from Uniprot.org