Tissue Specificity | Isoform 1, isoform 4 and isoform 5 are expressed in brain and placenta. |
Function | Bifunctional mitochondrial folate-interconverting enzyme that has both NAD/NADP-dependent methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. |
Protein Name | Bifunctional Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase 2 - MitochondrialNadp-Dependent Methylenetetrahydrofolate Dehydrogenase 2-Like ProteinMthfd2-Like Includes - Nad-Dependent Methylenetetrahydrofolate Dehydrogenase - Methenyltetrahydrofolate Cyclohydrolase |
Database Links | Reactome: R-HSA-196757 |
Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinMatrix Side |
Alternative Antibody Names | Anti-Bifunctional Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase 2 - Mitochondrial antibodyAnti-Nadp-Dependent Methylenetetrahydrofolate Dehydrogenase 2-Like Protein antibodyAnti-Mthfd2-Like Includes - Nad-Dependent Methylenetetrahydrofolate Dehydrogenase - Methenyltetrahydrofolate Cyclohydrolase antibodyAnti-MTHFD2L antibody |
Information sourced from Uniprot.org