Anti-MTHFD2 antibody (40-250) (STJ112422)

Name: Anti-MTHFD2 antibody (40-250) (STJ112422)
SKU: STJ112422
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ112422

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Short Description	Rabbit polyclonal MTHFD2 (40-250) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 IHC-P:1:50-1:200 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	MTHFD2
Gene ID	10797
Uniprot ID	MTDC_HUMAN
Immunogen Region	40-250
Immunogen Sequence	ISGRKLAQQIKQEVRQEVEE WVASGNKRPHLSVILVGENP ASHSYVLNKTRAAAVVGINS ETIMKPASISEEELLNLINK LNNDDNVDGLLVQLPLPEHI DERRICNAVSPDKDVDGFHV INVGRMCLDQYSMLPATPWG VWEIIKRTGIPTLGKNVVVA GRSKNVGMPIAMLLHTDGAH ERPGGDATVTISHRYTPKEQ LKKHTILADIV
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 40-250 of human MTHFD2 (NP_006627.2).

Function	Although its dehydrogenase activity is NAD-specific, it can also utilize NADP at a reduced efficiency.
Protein Name	Bifunctional Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase - Mitochondrial Includes - Nad-Dependent Methylenetetrahydrofolate Dehydrogenase - Methenyltetrahydrofolate Cyclohydrolase
Database Links	Reactome: R-HSA-196757
Cellular Localisation	Mitochondrion
Alternative Antibody Names	Anti-Bifunctional Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase - Mitochondrial Includes - Nad-Dependent Methylenetetrahydrofolate Dehydrogenase - Methenyltetrahydrofolate Cyclohydrolase antibody Anti-MTHFD2 antibody Anti-NMDMC antibody

Information sourced from Uniprot.org