| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-C-1-tetrahydrofolate synthase, cytoplasmic is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MTHFD1 |
| Gene ID: |
4522 |
| Uniprot ID: |
C1TC_HUMAN |
| Specificity: |
This antibody detects endogenous levels of MTHFD1 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human MTHFD1 |
| Function | Trifunctional enzyme that catalyzes the interconversion of three forms of one-carbon-substituted tetrahydrofolate: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate, 5,10-methenyltetrahydrofolate and (6S)-10-formyltetrahydrofolate. These derivatives of tetrahydrofolate are differentially required in nucleotide and amino acid biosynthesis, (6S)-10-formyltetrahydrofolate being required for purine biosynthesis while (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate is used for serine and methionine biosynthesis for instance. |
| Protein Name | C-1-Tetrahydrofolate Synthase - CytoplasmicC1-Thf SynthaseEpididymis Secretory Sperm Binding Protein Cleaved Into - C-1-Tetrahydrofolate Synthase - Cytoplasmic - N-Terminally Processed Includes - Methylenetetrahydrofolate Dehydrogenase - Methenyltetrahydrofolate Cyclohydrolase - Formyltetrahydrofolate Synthetase |
| Database Links | Reactome: R-HSA-196757 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-C-1-Tetrahydrofolate Synthase - Cytoplasmic antibodyAnti-C1-Thf Synthase antibodyAnti-Epididymis Secretory Sperm Binding Protein Cleaved Into - C-1-Tetrahydrofolate Synthase - Cytoplasmic - N-Terminally Processed Includes - Methylenetetrahydrofolate Dehydrogenase - Methenyltetrahydrofolate Cyclohydrolase - Formyltetrahydrofolate Synthetase antibodyAnti-MTHFD1 antibodyAnti-MTHFC antibodyAnti-MTHFD antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
