Anti-MTERFD1 antibody (69-300) (STJ111846)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MTERFD1 (69-300) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MTERF3 |
| Gene ID | 51001 |
| Uniprot ID | MTEF3_HUMAN |
| Immunogen Region | 69-300 |
| Immunogen Sequence | SSQSTSSSSQENNSAQSSLL PSMNEQSQKTQNISSFDSEL FLEELDELPPLSPMQPISEE EAIQIIADPPLPPASFTLRD YVDHSETLQKLVLLGVDLSK IEKHPEAANLLLRLDFEKDI KQMLLFLKDVGIEDNQLGAF LTKNHAIFSEDLENLKTRVA YLHSKNFSKADVAQMVRKAP FLLNFSVERLDNRLGFFQKE LELSVKKTRDLVVRLPRLLT GSLEPVKENMKV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 69-300 of human MTERFD1 (NP_057026.3). |
Additional Info
| Tissue Specificity | Highly expressed in heart, liver, kidney and testis. Detected at lower levels in brain, spleen and lung. |
| Function | Binds promoter DNA and regulates initiation of transcription. Required for normal mitochondrial transcription and translation, and for normal assembly of mitochondrial respiratory complexes. Required for normal mitochondrial function. Maintains 16S rRNA levels and functions in mitochondrial ribosome assembly by regulating the biogenesis of the 39S ribosomal subunit. |
| Protein Name | Transcription Termination Factor 3 - MitochondrialMitochondrial Transcription Termination Factor 3Mterf3Mterf Domain-Containing Protein 1 - Mitochondrial |
| Database Links | Reactome: R-HSA-5205685 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Transcription Termination Factor 3 - Mitochondrial antibodyAnti-Mitochondrial Transcription Termination Factor 3 antibodyAnti-Mterf3 antibodyAnti-Mterf Domain-Containing Protein 1 - Mitochondrial antibodyAnti-MTERF3 antibodyAnti-MTERFD1 antibodyAnti-CGI-12 antibody |
Information sourced from Uniprot.org