Anti-MTCH1 antibody (100-250) (STJ110366)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MTCH1 (100-250) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MTCH1 |
| Gene ID | 23787 |
| Uniprot ID | MTCH1_HUMAN |
| Immunogen Region | 100-250 |
| Immunogen Sequence | LYVKLLIQVGHEPMPPTLGT NVLGRKVLYLPSFFTYAKYI VQVDGKIGLFRGLSPRLMSN ALSTVTRGSMKKVFPPDEIE QVSNKDDMKTSLKKVVKETS YEMMMQCVSRMLAHPLHVIS MRCMVQFVGREAKYSGVLSS IGKIFKEEGLL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 100-250 of human MTCH1 (NP_001258570.1). |
Additional Info
| Tissue Specificity | Widely expressed with a predominant expression in brain. |
| Function | Protein insertase that mediates insertion of transmembrane proteins into the mitochondrial outer membrane. Catalyzes insertion of proteins with alpha-helical transmembrane regions, such as signal-anchored, tail-anchored and multi-pass membrane proteins. Does not mediate insertion of beta-barrel transmembrane proteins. May play a role in apoptosis. |
| Protein Name | Mitochondrial Carrier Homolog 1Presenilin-Associated Protein |
| Database Links | |
| Cellular Localisation | Mitochondrion Outer MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Carrier Homolog 1 antibodyAnti-Presenilin-Associated Protein antibodyAnti-MTCH1 antibodyAnti-PSAP antibodyAnti-CGI-64 antibodyAnti-UNQ1871 antibodyAnti-PRO4314 antibody |
Information sourced from Uniprot.org