Anti-MTAP antibody (aa97-196) [ZR467] (STJ180680)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant human MTAP protein fragment (aa97-196)
General Information
| Short Description | Rabbit monoclonal MTAP (aa97-196) antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ZR467 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purified |
| Dilution Range | 1:100-200 |
| Formulation | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Storage Instruction | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
Target Information
| Gene Symbol | MTAP |
| Gene ID | 4507 |
| Uniprot ID | MTAP_HUMAN |
| Immunogen | Recombinant human MTAP protein fragment (aa97-196) |
| Immunogen Region | aa97-196 |
| Specificity | Positive Control: Urothelial carcinoma |
Additional Info
| Tissue Specificity | Ubiquitously expressed. |
| Function | Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. |
| Protein Name | S-Methyl-5'-Thioadenosine Phosphorylase5'-Methylthioadenosine PhosphorylaseMta PhosphorylaseMtapMtapase |
| Database Links | Reactome: R-HSA-1237112Reactome: R-HSA-8950505 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-S-Methyl-5'-Thioadenosine Phosphorylase antibodyAnti-5'-Methylthioadenosine Phosphorylase antibodyAnti-Mta Phosphorylase antibodyAnti-Mtap antibodyAnti-Mtapase antibodyAnti-MTAP antibodyAnti-MSAP antibody |
Information sourced from Uniprot.org