Anti-MTA3 antibody (270-320) (STJA0006524)

SKU:
STJA0006524
£49.00 - £261.00
Processing The item has been added

Short Description :Rabbit polyclonal anti-Metastasis-associated protein MTA3 (270-320) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:1000-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:MTA3
Gene ID:57504
Uniprot ID:MTA3_HUMAN
Immunogen:Synthesized peptide derived from human MTA3 AA range: 270-320
Immunogen Region:270-320
Specificity:This antibody detects endogenous levels of human MTA3
Function Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6.
Protein Name Metastasis-Associated Protein Mta3
Database Links Reactome: R-HSA-3214815
Reactome: R-HSA-427389
Reactome: R-HSA-73762
Reactome: R-HSA-8943724
Reactome: R-HSA-9679191
Reactome: R-HSA-9843940
Reactome: R-HSA-9844594
Reactome: R-HSA-9845323
Cellular Localisation Nucleus
Cytoplasm
Alternative Antibody Names Anti-Metastasis-Associated Protein Mta3 antibody
Anti-MTA3 antibody
Anti-KIAA1266 antibody

Information sourced from Uniprot.org