![Immunofluorescence analysis of U-2 OS cells using [KO Validated] MTA2 Rabbit monoclonal antibody (STJ11102119) at dilution of 1 : 100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/91036/361850/STJ11102119_2__16220.1713126765.jpg?c=1 "Immunofluorescence analysis of U-2 OS cells using [KO Validated] MTA2 Rabbit monoclonal antibody (STJ11102119) at dilution of 1 : 100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.")
![Western blot analysis of lysates from wild type (WT) and MTA2 knockout (KO) 293T cells, using [KO Validated] MTA2 Rabbit monoclonal antibody (STJ11102119) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/91036/361852/STJ11102119_4__66670.1713126767.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and MTA2 knockout (KO) 293T cells, using [KO Validated] MTA2 Rabbit monoclonal antibody (STJ11102119) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.")
Anti-MTA2 antibody (569-668) [S9MR] (STJ11102119)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal MTA2 (569-668) antibody for use in WB, IHC-P, IF, ICC, ELISA and ChIP in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA/ChIP |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S9MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.ChIP:5 Mu g antibody for 10 Mu g-15 Mu g of Chromat |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MTA2 |
| Gene ID | 9219 |
| Uniprot ID | MTA2_HUMAN |
| Immunogen Region | 569-668 |
| Immunogen Sequence | GVPFSANGRPLASGIRSSSQ PAAKRQKLNPADAPNPVVFV ATKDTRALRKALTHLEMRRA ARRPNLPLKVKPTLIAVRPP VPLPAPSHPASTNEPIVLED |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 569-668 of human MTA2 (O94776). |
Additional Info
| Tissue Specificity | Widely expressed. |
| Function | May function as a transcriptional coregulator. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. |
| Protein Name | Metastasis-Associated Protein Mta2Metastasis-Associated 1-Like 1Mta1-L1 ProteinP53 Target Protein In Deacetylase Complex |
| Database Links | Reactome: R-HSA-3214815Reactome: R-HSA-427389Reactome: R-HSA-6804758Reactome: R-HSA-73762Reactome: R-HSA-8943724Reactome: R-HSA-9679191Reactome: R-HSA-9843940Reactome: R-HSA-9844594Reactome: R-HSA-9845323 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Metastasis-Associated Protein Mta2 antibodyAnti-Metastasis-Associated 1-Like 1 antibodyAnti-Mta1-L1 Protein antibodyAnti-P53 Target Protein In Deacetylase Complex antibodyAnti-MTA2 antibodyAnti-MTA1L1 antibodyAnti-PID antibody |
Information sourced from Uniprot.org