![Western blot analysis of lysates from wild type (WT) and MTA2 knockout (KO) 293T cells, using [KO Validated] MTA2 Rabbit polyclonal antibody (STJ24625) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/100090/386123/STJ24625_2__95252.1713155126.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and MTA2 knockout (KO) 293T cells, using [KO Validated] MTA2 Rabbit polyclonal antibody (STJ24625) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
Anti-MTA2 antibody (60-180) (STJ24625)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MTA2 (60-180) antibody for use in WB, ELISA and ChIP in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/ChIP |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.ChIP:5 Mu g antibody for 10 Mu g-15 Mu g of Chromatin |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MTA2 |
| Gene ID | 9219 |
| Uniprot ID | MTA2_HUMAN |
| Immunogen Region | 60-180 |
| Immunogen Sequence | DSNAREFEEESKQPGVSEQQ RHQLKHRELFLSRQFESLPA THIRGKCSVTLLNETDILSQ YLEKEDCFFYSLVFDPVQKT LLADQGEIRVGCKYQAEIPD RLVEGESDNRNQQKMEMKVW D |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 60-180 of human MTA2 (NP_004730.2). |
Additional Info
| Tissue Specificity | Widely expressed. |
| Function | May function as a transcriptional coregulator. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. |
| Protein Name | Metastasis-Associated Protein Mta2Metastasis-Associated 1-Like 1Mta1-L1 ProteinP53 Target Protein In Deacetylase Complex |
| Database Links | Reactome: R-HSA-3214815Reactome: R-HSA-427389Reactome: R-HSA-6804758Reactome: R-HSA-73762Reactome: R-HSA-8943724Reactome: R-HSA-9679191Reactome: R-HSA-9843940Reactome: R-HSA-9844594Reactome: R-HSA-9845323 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Metastasis-Associated Protein Mta2 antibodyAnti-Metastasis-Associated 1-Like 1 antibodyAnti-Mta1-L1 Protein antibodyAnti-P53 Target Protein In Deacetylase Complex antibodyAnti-MTA2 antibodyAnti-MTA1L1 antibodyAnti-PID antibody |
Information sourced from Uniprot.org