Anti-MT-ATP8 antibody (45-58) (STJ119897)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MT-ATP8 (45-58) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:100IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MT-ATP8 |
| Gene ID | 4509 |
| Uniprot ID | ATP8_HUMAN |
| Immunogen Region | 45-58 |
| Immunogen Sequence | MPQLNTTVWPTMITPMLLTL FLITQLKMLNTNYHLPPSPK PMKMKNYNKPWEPKWTKICS LHSLPPQS |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-68 of human MT-ATP8 (YP_003024030.1). |
Additional Info
| Function | Subunit 8, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (Probable). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain. |
| Protein Name | Atp Synthase F(0 Complex Subunit 8A6lF-Atpase Subunit 8 |
| Database Links | Reactome: R-HSA-163210Reactome: R-HSA-8949613 |
| Cellular Localisation | Mitochondrion MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Atp Synthase F(0 Complex Subunit 8 antibodyAnti-A6l antibodyAnti-F-Atpase Subunit 8 antibodyAnti-MT-ATP8 antibodyAnti-ATP8 antibodyAnti-ATPASE8 antibodyAnti-MTATP8 antibody |
Information sourced from Uniprot.org