Anti-MS4A1 antibody (197-297) (STJ24609)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CD20 (197-297) antibody for use in WB, IHC-P, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MS4A1 |
| Gene ID | 931 |
| Uniprot ID | CD20_HUMAN |
| Immunogen Region | 197-297 |
| Immunogen Sequence | MLIFAFFQELVIAGIVENEW KRTCSRPKSNIVLLSAEEKK EQTIEIKEEVVGLTETSSQP KNEEDIEIIPIQEEEEEETE TNFPEPPQDQESSPIENDSS P |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 197-297 of human CD20 (NP_068769.2). |
Additional Info
| Tissue Specificity | Expressed on B-cells. |
| Post Translational Modifications | Phosphorylated on serines and threonines in resting B-cells. Protein kinase C/PKC can use CD20 as substrate. |
| Function | B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. |
| Protein Name | B-Lymphocyte Antigen Cd20B-Lymphocyte Surface Antigen B1Bp35Leukocyte Surface Antigen Leu-16Membrane-Spanning 4-Domains Subfamily A Member 1Cd Antigen Cd20 |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLipid-AnchorConstitutively Associated With Membrane Rafts |
| Alternative Antibody Names | Anti-B-Lymphocyte Antigen Cd20 antibodyAnti-B-Lymphocyte Surface Antigen B1 antibodyAnti-Bp35 antibodyAnti-Leukocyte Surface Antigen Leu-16 antibodyAnti-Membrane-Spanning 4-Domains Subfamily A Member 1 antibodyAnti-Cd Antigen Cd20 antibodyAnti-MS4A1 antibodyAnti-CD20 antibody |
Information sourced from Uniprot.org