Anti-MRPL41 antibody (81-130) (STJ94228)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human MRPL41. AA range:81-130
General Information
| Short Description | Rabbit polyclonal anti-Large ribosomal subunit protein mL41 (81-130) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MRPL41 |
| Gene ID | 64975 |
| Uniprot ID | RM41_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MRPL41. AA range:81-130 |
| Immunogen Region | 81-130 |
| Specificity | MRP-L41 Polyclonal Antibody detects endogenous levels of MRP-L41 protein. |
Additional Info
| Tissue Specificity | Present in kidney, liver, thymus and testis, and at lower level in brain and spleen (at protein level). |
| Function | Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins. |
| Protein Name | Large Ribosomal Subunit Protein Ml4139s Ribosomal Protein L41 - MitochondrialL41mtMrp-L41Bcl-2-Interacting Mitochondrial Ribosomal Protein L41Cell Proliferation-Inducing Gene 3 ProteinMrp-L27 Homolog |
| Database Links | Reactome: R-HSA-5368286Reactome: R-HSA-5389840Reactome: R-HSA-5419276 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Large Ribosomal Subunit Protein Ml41 antibodyAnti-39s Ribosomal Protein L41 - Mitochondrial antibodyAnti-L41mt antibodyAnti-Mrp-L41 antibodyAnti-Bcl-2-Interacting Mitochondrial Ribosomal Protein L41 antibodyAnti-Cell Proliferation-Inducing Gene 3 Protein antibodyAnti-Mrp-L27 Homolog antibodyAnti-MRPL41 antibodyAnti-BMRP antibodyAnti-MRPL27 antibodyAnti-RPML27 antibodyAnti-PIG3 antibody |
Information sourced from Uniprot.org