• Immunohistochemistry of rat spleen with Anti-MRP1 primary antibody (STJ501801) at 1:100 dilution in Buffer. Section was treated with DAB and Haematoxylin stain. Magnification is at 40X.

Anti-MRP1 antibody (STJ501801)

SKU:
STJ501801-100

£441.50
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Host: Rabbit
Applications: ELISA/IHC/IP/WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MRP1 is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.5 µg/µl
Dilution Range: WB: 1:500
ELISA: 1:20, 000
IP: 1:200
IHC: 1:100
ICC: 1:100
IF: 1:100
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Abcc1
Gene ID: 24565
Uniprot ID: MRP1_RAT
Immunogen: Synthetic peptide corresponding to unique amino acid sequences on rat multidrug resistance-associated protein 1.
Tissue Specificity Skeletal muscle, brain, heart, spleen, lung and kidney.
Post Translational Modifications Glycosylated.
Function Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export. Hydrolyzes ATP with low efficiency. Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation. Participates in inflammatory response by allowing export of leukotriene C4 from leukotriene C4-synthezing cells.
Protein Name Multidrug Resistance-Associated Protein 1
Atp-Binding Cassette Sub-Family C Member 1
Glutathione-S-Conjugate-Translocating Atpase Abcc1
Leukotriene C(4 Transporter
Ltc4 Transporter
Database Links Reactome: R-RNO-189483
Reactome: -RNO-2142691
Reactome: -RNO-382556
Reactome: -RNO-9707564
Reactome: -RNO-9753281
Reactome: -RNO-9758890
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Multidrug Resistance-Associated Protein 1 antibody
Anti-Atp-Binding Cassette Sub-Family C Member 1 antibody
Anti-Glutathione-S-Conjugate-Translocating Atpase Abcc1 antibody
Anti-Leukotriene C(4 Transporter antibody
Anti-Ltc4 Transporter antibody
Anti-Abcc1 antibody
Anti-Mrp1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance