Anti-MRM2 antibody (STJA0009284)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human FTSJ2
General Information
| Short Description | Rabbit polyclonal anti-rRNA methyltransferase 2, mitochondrial-2 O-methyltransferase for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MRM2 |
| Gene ID | 29960 |
| Uniprot ID | MRM2_HUMAN |
| Immunogen | Synthesized peptide derived from human FTSJ2 |
| Specificity | This antibody detects endogenous levels of FTSJ2 at Human, Mouse |
Additional Info
| Function | S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1369 (Um1369) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. This activity may require prior 2'-O-methylguanosine modification at position 1370 (Gm1370) by MRM3. Essential for late-stage assembly of mtLSU required for efficient translation of mitochondrial DNA encoded proteins.methyltransferase activity is not required for this function. Essential for mitochondrial respiratory function. |
| Protein Name | Rrna Methyltransferase 2 - Mitochondrial16s RrnaUridine(1369-2'-O-Methyltransferase16s Rrna Um1369 2'-O-MethyltransferaseProtein Ftsj Homolog 2 |
| Database Links | Reactome: R-HSA-6793080 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Rrna Methyltransferase 2 - Mitochondrial antibodyAnti-16s Rrna antibodyAnti-Uridine(1369-2'-O-Methyltransferase antibodyAnti-16s Rrna Um1369 2'-O-Methyltransferase antibodyAnti-Protein Ftsj Homolog 2 antibodyAnti-MRM2 antibodyAnti-FJH1 antibodyAnti-FTSJ2 antibody |
Information sourced from Uniprot.org