| Function | Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover. |
| Protein Name | Methylthioribose-1-Phosphate IsomeraseM1piMtr-1-P IsomeraseMediator Of Rhoa-Dependent InvasionS-Methyl-5-Thioribose-1-Phosphate IsomeraseTranslation Initiation Factor Eif-2b Subunit Alpha/Beta/Delta-Like Protein |
| Database Links | Reactome: R-HSA-1237112 |
| Cellular Localisation | NucleusCytoplasmCell ProjectionPrimarily NuclearBut Cytoplasmic In Cancer CellsWith Enrichment At Leading Edge Of The Plasma Membrane In Late Stage Tumor Cells |
| Alternative Antibody Names | Anti-Methylthioribose-1-Phosphate Isomerase antibodyAnti-M1pi antibodyAnti-Mtr-1-P Isomerase antibodyAnti-Mediator Of Rhoa-Dependent Invasion antibodyAnti-S-Methyl-5-Thioribose-1-Phosphate Isomerase antibodyAnti-Translation Initiation Factor Eif-2b Subunit Alpha/Beta/Delta-Like Protein antibodyAnti-MRI1 antibodyAnti-MRDI antibodyAnti-UNQ6390 antibodyAnti-PRO21135 antibody |
Information sourced from Uniprot.org
