| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DHPS (1-369) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DHPS |
| Gene ID: |
1725 |
| Uniprot ID: |
DHYS_HUMAN |
| Immunogen Region: |
1-369 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-369 of human DHPS (NP_001921.1). |
| Immunogen Sequence: |
MEGSLEREAPAGALAAVLKH SSTLPPESTQVRGYDFNRGV NYRALLEAFGTTGFQATNFG RAVQQVNAMIEKKLEPLSQD EDQHADLTQSRRPLTSCTIF LGYTSNLISSGIRETIRYLV QHNMVDVLVTTAGGVEEDLI KCLAPTYLGEFSLRGKELRE NGINRIGNLLVPNENYCKFE DWLMPILDQMVMEQNTEGVK WTPSKMIARLGKEINNPESV YYWAQKNHIPVFSPALTDG |
| Function | Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a critical lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. This is the first step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function. |
| Protein Name | Deoxyhypusine SynthaseDhs |
| Database Links | Reactome: R-HSA-204626 |
| Alternative Antibody Names | Anti-Deoxyhypusine Synthase antibodyAnti-Dhs antibodyAnti-DHPS antibodyAnti-DS antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
