Anti-DHPS antibody (1-369) (STJ28450)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DHPS (1-369) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DHPS |
| Gene ID | 1725 |
| Uniprot ID | DHYS_HUMAN |
| Immunogen Region | 1-369 |
| Immunogen Sequence | MEGSLEREAPAGALAAVLKH SSTLPPESTQVRGYDFNRGV NYRALLEAFGTTGFQATNFG RAVQQVNAMIEKKLEPLSQD EDQHADLTQSRRPLTSCTIF LGYTSNLISSGIRETIRYLV QHNMVDVLVTTAGGVEEDLI KCLAPTYLGEFSLRGKELRE NGINRIGNLLVPNENYCKFE DWLMPILDQMVMEQNTEGVK WTPSKMIARLGKEINNPESV YYWAQKNHIPVFSPALTDG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-369 of human DHPS (NP_001921.1). |
Additional Info
| Function | Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a critical lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. This is the first step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function. |
| Protein Name | Deoxyhypusine SynthaseDhs |
| Database Links | Reactome: R-HSA-204626 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Deoxyhypusine Synthase antibodyAnti-Dhs antibodyAnti-DHPS antibodyAnti-DS antibody |
Information sourced from Uniprot.org