Anti-MRGPRX3/MRGX3 antibody (Internal) (STJ71906)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-MRGPRX3/MRGX3 (Internal) is suitable for use in ELISA research applications. |
| Applications | Pep-ELISA |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Not yet tested. At this stage we are dependent on researchers in the field for further characterization of this product. Therefore we cannot recommend an optimal concentration and the a |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | MRGPRX3 |
| Gene ID | 117195 |
| Uniprot ID | MRGX3_HUMAN |
| Accession Number | NP_473372.2 |
| Immunogen Region | Internal |
| Immunogen Sequence | QLPQETLELSGSRL |
| Specificity | This antibody may cross-react with human MRGPRX1 and X4 (GeneID: 259249, 117196; MW: 36.25kDa and 36.43kDa). |
Additional Info
| Function | Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins. |
| Protein Name | Mas-Related G-Protein Coupled Receptor Member X3Sensory Neuron-Specific G-Protein Coupled Receptor 1/2 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mas-Related G-Protein Coupled Receptor Member X3 antibodyAnti-Sensory Neuron-Specific G-Protein Coupled Receptor 1/2 antibodyAnti-MRGPRX3 antibodyAnti-MRGX3 antibodyAnti-SNSR1 antibodyAnti-SNSR2 antibody |
Information sourced from Uniprot.org