Anti-MRC1 antibody (1357-1456) [S8MR] (STJ11101288)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Mannose Receptor/CD206 (1357-1456) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S8MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MRC1 |
| Gene ID | 4360 |
| Uniprot ID | MRC1_HUMAN |
| Immunogen Region | 1357-1456 |
| Immunogen Sequence | RPKIIDAKPTHELLTTKADT RKMDPSKPSSNVAGVVIIVI LLILTGAGLAAYFFYKKRRV HLPQEGAFENTLYFNSQSSP GTSDMKDLVGNIEQNEHSVI |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1357-1456 of human Mannose Receptor/CD206 (P22897). |
Additional Info
| Function | Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. (Microbial infection) Acts as a phagocytic receptor for bacteria, fungi and other pathogens. (Microbial infection) Acts as a receptor for Dengue virus envelope protein E. (Microbial infection) Interacts with Hepatitis B virus envelope protein. |
| Protein Name | Macrophage Mannose Receptor 1MmrC-Type Lectin Domain Family 13 Member DC-Type Lectin Domain Family 13 Member D-LikeHuman Mannose ReceptorHmrMacrophage Mannose Receptor 1-Like Protein 1Cd Antigen Cd206 |
| Database Links | Reactome: R-HSA-1236978Reactome: R-HSA-9637628 |
| Cellular Localisation | Endosome MembraneSingle-Pass Type I Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Macrophage Mannose Receptor 1 antibodyAnti-Mmr antibodyAnti-C-Type Lectin Domain Family 13 Member D antibodyAnti-C-Type Lectin Domain Family 13 Member D-Like antibodyAnti-Human Mannose Receptor antibodyAnti-Hmr antibodyAnti-Macrophage Mannose Receptor 1-Like Protein 1 antibodyAnti-Cd Antigen Cd206 antibodyAnti-MRC1 antibodyAnti-CLEC13D antibodyAnti-CLEC13DL antibodyAnti-MRC1L1 antibody |
Information sourced from Uniprot.org