• Western blot with Anti-MRAP2 Antibody (STJ501793) with cDNA transfected MRAP (A) and control transfected MRAP (B), at 1:500 dilution in buffer.

Anti-MRAP2 antibody (70-120) (STJ501793)

SKU:
STJ501793-100

£441.50
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Host: Rabbit
Applications: CM/ELISA/ICC/IF/IHC/IP/WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MRAP2 (70-120) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.60-0.61 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
IHC: 1:200
ICC: 1:200
IF: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Mrap
Gene ID: 77037
Uniprot ID: MRAP_MOUSE
Immunogen Region: 70-120
Immunogen: Synthetic peptide taken within amino acid region 70-120 on mouse Melanocortin-2 receptor accessory protein.
Tissue Specificity Largely restricted to fat tissues. Predominantly expressed in mouse epididymal (white adipose tissue) and interscapular (brown adipose tissue) fat pads. Expression is weak or absent in lung, spleen, intestine, kidney, heart and skeletal muscle.
Function Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R). Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH). May be involved in the intracellular trafficking pathways in adipocyte cells.
Protein Name Melanocortin-2 Receptor Accessory Protein
Fat Cell-Specific Low Molecular Weight Protein
Fat Tissue-Specific Low Mw Protein
Cellular Localisation Cell Membrane
Single-Pass Membrane Protein
Endoplasmic Reticulum Membrane
The Formation Of Antiparallel Homo- And Heterodimers Suggest That N- And C-Terminus Can Both Localize In The Cytoplasmic And Extracellular Parts
Depending On The Context
Upon Insulin Stimulation
It Is Redistributed Into Spotty Structures Throughout The Cytoplasm
Alternative Antibody Names Anti-Melanocortin-2 Receptor Accessory Protein antibody
Anti-Fat Cell-Specific Low Molecular Weight Protein antibody
Anti-Fat Tissue-Specific Low Mw Protein antibody
Anti-Mrap antibody
Anti-Falp antibody

Information sourced from Uniprot.org

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