• Western blot analysis of extracts of various cell lines, using Myelin Protein Zero (MPZ) antibody (STJ24606) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
  • Western blot analysis of extracts of Mouse spinal cord, using Myelin Protein Zero (MPZ) antibody (STJ24606) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-MPZ antibody (30-248) (STJ24606)

SKU:
STJ24606

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MPZ (30-248) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MPZ
Gene ID: 4359
Uniprot ID: MYP0_HUMAN
Immunogen Region: 30-248
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-248 of human Myelin Protein Zero (MPZ) (NP_000521.2).
Immunogen Sequence: IVVYTDREVHGAVGSRVTLH CSFWSSEWVSDDISFTWRYQ PEGGRDAISIFHYAKGQPYI DEVGTFKERIQWVGDPRWKD GSIVIHNLDYSDNGTFTCDV KNPPDIVGKTSQVTLYVFEK VPTR
Tissue Specificity Found only in peripheral nervous system Schwann cells.
Post Translational Modifications N-glycosylated.contains sulfate-substituted glycan.
Function Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction.
Protein Name Myelin Protein P0
Myelin Peripheral Protein
Mpp
Myelin Protein Zero
Database Links Reactome: R-HSA-9619665
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Isoform L-Mpz: Myelin Membrane
Alternative Antibody Names Anti-Myelin Protein P0 antibody
Anti-Myelin Peripheral Protein antibody
Anti-Mpp antibody
Anti-Myelin Protein Zero antibody
Anti-MPZ antibody

Information sourced from Uniprot.org

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