| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MPZ (30-248) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MPZ |
| Gene ID: |
4359 |
| Uniprot ID: |
MYP0_HUMAN |
| Immunogen Region: |
30-248 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 30-248 of human Myelin Protein Zero (MPZ) (NP_000521.2). |
| Immunogen Sequence: |
IVVYTDREVHGAVGSRVTLH CSFWSSEWVSDDISFTWRYQ PEGGRDAISIFHYAKGQPYI DEVGTFKERIQWVGDPRWKD GSIVIHNLDYSDNGTFTCDV KNPPDIVGKTSQVTLYVFEK VPTR |
| Tissue Specificity | Found only in peripheral nervous system Schwann cells. |
| Post Translational Modifications | N-glycosylated.contains sulfate-substituted glycan. |
| Function | Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction. |
| Protein Name | Myelin Protein P0Myelin Peripheral ProteinMppMyelin Protein Zero |
| Database Links | Reactome: R-HSA-9619665 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinIsoform L-Mpz: Myelin Membrane |
| Alternative Antibody Names | Anti-Myelin Protein P0 antibodyAnti-Myelin Peripheral Protein antibodyAnti-Mpp antibodyAnti-Myelin Protein Zero antibodyAnti-MPZ antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
