Anti-Monoamine Oxidase A antibody (Internal) (STJ70775)

SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
STJ70775-100
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General Information

Short DescriptionGoat polyclonal antibody anti-Monoamine Oxidase A (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
ApplicationsPep-ELISA/WB/IHC
HostGoat
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration0.5 mg/mL
PurificationPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Dilution RangePeptide ELISA: antibody detection limit dilution 1:64000.
WB: Approx 70kDa band observed in Human Heart lysates (calculated MW of 60.0kDa according to NP_000231.1). The user is warned for non-specific background in Western blot. Recommended conce
Formulation0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Storage InstructionStore at-20ยฐC on receipt and minimise freeze-thaw cycles.

Target Information

Gene SymbolMAOA
Gene ID4128
Uniprot IDAOFA_HUMAN
Accession NumberNP_000231.1
Immunogen RegionInternal
Immunogen SequenceDAPWEAQHADKWDK

Additional Info

Function Catalyzes the oxidative deamination of primary and some secondary amine such as neurotransmitters, with concomitant reduction of oxygen to hydrogen peroxide and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. Preferentially oxidizes serotonin. Also catalyzes the oxidative deamination of kynuramine to 3-(2-aminophenyl)-3-oxopropanal that can spontaneously condense to 4-hydroxyquinoline.
Protein Name Amine Oxidase Flavin-Containing A
Monoamine Oxidase Type A
Mao-A
Database Links Reactome: R-HSA-141333
Reactome: R-HSA-181430
Reactome: R-HSA-379397
Reactome: R-HSA-379398
Reactome: R-HSA-379401
Reactome: R-HSA-380612
Reactome: R-HSA-5579012
Reactome: R-HSA-6785807
Cellular Localisation Mitochondrion Outer Membrane
Single-Pass Type Iv Membrane Protein
Cytoplasmic Side
Alternative Antibody Names Anti-Amine Oxidase Flavin-Containing A antibody
Anti-Monoamine Oxidase Type A antibody
Anti-Mao-A antibody
Anti-MAOA antibody

Information sourced from Uniprot.org

Citations

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