Anti-MON1A antibody (1-250 aa) (STJ119930)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MON1A (1-250 aa) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20Β°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MON1A |
| Gene ID | 84315 |
| Uniprot ID | MON1A_HUMAN |
| Immunogen Region | 1-250 aa |
| Immunogen Sequence | MHPGGGPSRAERLELGLGRE RPAKAIFLHRRPGEGGGRER CLRCGHVCVRRGPGPREAVP SGRPRPDTLTPPWVRQRAVT GTFCASWTPLRNRRAQRMAT DMQRKRSSECLDGTLTPSDG QSMERAESPTPGMAQGMEPG AGQEGAMFVHARSYEDLTES EDGAASGDSHKEGTRGPPPL PTDMRQISQDFSELSTQLTG VARDLQEEMLPGSSEDWLEP PGAVGRPATEPPREGTTEG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human MON1A. (Q86VX9). |
Additional Info
| Function | Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes. Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form. |
| Protein Name | Vacuolar Fusion Protein Mon1 Homolog A |
| Database Links | Reactome: R-HSA-8876198 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Vacuolar Fusion Protein Mon1 Homolog A antibodyAnti-MON1A antibodyAnti-SAND1 antibody |
Information sourced from Uniprot.org