Anti-MOK antibody (1-230) (STJ25285)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MOK (1-230) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MOK |
| Gene ID | 5891 |
| Uniprot ID | MOK_HUMAN |
| Immunogen Region | 1-230 |
| Immunogen Sequence | MKNYKAIGKIGEGTFSEVMK MQSLRDGNYYACKQMKQRFE SIEQVNNLREIQALRRLNPH PNILMLHEVVFDRKSGSLAL ICELMDMNIYELIRGRRYPL SEKKIMHYMYQLCKSLDHIH RNGIFHRDVKPENILIKQDV LKLGDFGSCRSVYSKQPYTE YISTRWYRAPECLLTDGFYT YKMDLWSAGCVFYEIASLQP LFPGVNELDQISKIHDVIGT PAQKILTKFK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human MOK (NP_055041.1). |
Additional Info
| Tissue Specificity | Expressed in heart, brain, lung, kidney, and pancreas, and at very low levels in placenta, liver and skeletal muscle. Detected in retina. |
| Post Translational Modifications | Autophosphorylated. |
| Function | Able to phosphorylate several exogenous substrates and to undergo autophosphorylation. Negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner. |
| Protein Name | Mapk/Mak/Mrk Overlapping KinaseMok Protein KinaseRenal Tumor Antigen 1Rage-1 |
| Database Links | |
| Cellular Localisation | CytoplasmCell ProjectionCiliumNucleus |
| Alternative Antibody Names | Anti-Mapk/Mak/Mrk Overlapping Kinase antibodyAnti-Mok Protein Kinase antibodyAnti-Renal Tumor Antigen 1 antibodyAnti-Rage-1 antibodyAnti-MOK antibodyAnti-RAGE antibodyAnti-RAGE1 antibody |
Information sourced from Uniprot.org