Anti-MNDA antibody (358-407) (STJ94168)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human MNDA. AA range:358-407
General Information
| Short Description | Rabbit polyclonal anti-Myeloid cell nuclear differentiation antigen (358-407) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MNDA |
| Gene ID | 4332 |
| Uniprot ID | MNDA_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MNDA. AA range:358-407 |
| Immunogen Region | 358-407 |
| Specificity | MNDA Polyclonal Antibody detects endogenous levels of MNDA protein. |
Additional Info
| Tissue Specificity | Expressed constitutively in cells of the myeloid lineage. Found in promyelocyte stage cells as well as in all other stage cells including peripheral blood monocytes and granulocytes. Also appears in myeloblast cells in some cases of acute myeloid Leukemia. |
| Function | May act as a transcriptional activator/repressor in the myeloid lineage. Plays a role in the granulocyte/monocyte cell-specific response to interferon. Stimulates the DNA binding of the transcriptional repressor protein YY1. |
| Protein Name | Myeloid Cell Nuclear Differentiation Antigen |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | NucleusCytoplasmUniformly Distributed Throughout The Interphase Cell NucleusAssociates With Chromatin |
| Alternative Antibody Names | Anti-Myeloid Cell Nuclear Differentiation Antigen antibodyAnti-MNDA antibody |
Information sourced from Uniprot.org