Anti-MMRN2 antibody (133-183 aa) (STJ193664)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human MMRN2 at the amino acid range 133-183
General Information
| Short Description | Rabbit polyclonal anti-Multimerin-2 (133-183 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MMRN2 |
| Gene ID | 79812 |
| Uniprot ID | MMRN2_HUMAN |
| Immunogen | Synthesized peptide derived from the human MMRN2 at the amino acid range 133-183 |
| Immunogen Region | 133-183 aa |
| Specificity | This antibody detects endogenous levels of MMRN2 at Human/Mouse |
Additional Info
| Post Translational Modifications | N- and O-glycosylated. O-fucosylated within the EMI domain (at Ser-63, Thr-67 and Thr-115) by FUT10/POFUT3 and FUT11/POFUT4. Processed by matrix metalloproteinases (MMPs) including MMP9 and, to a lesser degree, by MMP2 upon angiogenic stimulation. |
| Function | Extracellular matrix protein that plays significant roles in the vascular system and is required for the maintenance and stability of blood vessel. Affects several essential steps in angiogenesis including endothelial cell proliferation, migration, and tube formation. Positively regulates angiogenesis by acting as a ligand for CD93 receptor. |
| Protein Name | Multimerin-2Emilin-3Elastin Microfibril Interface Located Protein 3Elastin Microfibril Interfacer 3Endoglyx-1 P125/P140 Subunit |
| Database Links | |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Multimerin-2 antibodyAnti-Emilin-3 antibodyAnti-Elastin Microfibril Interface Located Protein 3 antibodyAnti-Elastin Microfibril Interfacer 3 antibodyAnti-Endoglyx-1 P125/P140 Subunit antibodyAnti-MMRN2 antibodyAnti-EMILIN3 antibody |
Information sourced from Uniprot.org