| Host: |
Mouse |
| Applications: |
IHC/IF |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-MMP9 is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
SM0375 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG2ak |
| Formulation: |
PBS with 0.15% ProClin300, 100 Mu g/mL BSA and 50% glycerol. |
| Purification: |
Affinity purification |
| Dilution Range: |
IHC/IF (H) 1:300-1:600 |
| Storage Instruction: |
Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
| Gene Symbol: |
MMP9 |
| Gene ID: |
4318 |
| Uniprot ID: |
MMP9_HUMAN |
| Immunogen: |
Recombinant protein corresponding to Human MMP9 |
| Post Translational Modifications | Processing of the precursor yields different active forms of 64, 67 and 82 kDa. Sequentially processing by MMP3 yields the 82 kDa matrix metalloproteinase-9. N- and O-glycosylated. |
| Function | Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves NINJ1 to generate the Secreted ninjurin-1 form. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. |
| Protein Name | Matrix Metalloproteinase-9Mmp-992 Kda Gelatinase92 Kda Type Iv CollagenaseGelatinase BGelb Cleaved Into - 67 Kda Matrix Metalloproteinase-9 - 82 Kda Matrix Metalloproteinase-9 |
| Database Links | Reactome: R-HSA-1433557Reactome: R-HSA-1442490Reactome: R-HSA-1474228Reactome: R-HSA-1592389Reactome: R-HSA-2022090Reactome: R-HSA-3928665Reactome: R-HSA-6785807Reactome: R-HSA-6798695Reactome: R-HSA-9009391 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Matrix Metalloproteinase-9 antibodyAnti-Mmp-9 antibodyAnti-92 Kda Gelatinase antibodyAnti-92 Kda Type Iv Collagenase antibodyAnti-Gelatinase B antibodyAnti-Gelb Cleaved Into - 67 Kda Matrix Metalloproteinase-9 - 82 Kda Matrix Metalloproteinase-9 antibodyAnti-MMP9 antibodyAnti-CLG4B antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
