• Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MMP-16 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from HepG2 cells, using MMP-16 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using MMP-16 Polyclonal Antibody diluted at 1：500

Anti-MMP16 antibody (551-600) (STJ94277)

SKU:
STJ94277

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Matrix metalloproteinase-16 (551-600) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MMP16
Gene ID: 4325
Uniprot ID: MMP16_HUMAN
Immunogen Region: 551-600
Specificity: MMP-16 Polyclonal Antibody detects endogenous levels of MMP-16 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human MMP-16. AA range:551-600
Tissue Specificity Expressed in heart, brain, placenta, ovary and small intestine. Isoform Short is found in the ovary.
Post Translational Modifications The precursor is cleaved by a furin endopeptidase.
Function Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.
Protein Name Matrix Metalloproteinase-16
Mmp-16
Mmp-X2
Membrane-Type Matrix Metalloproteinase 3
Mt-Mmp 3
Mtmmp3
Membrane-Type-3 Matrix Metalloproteinase
Mt3-Mmp
Mt3mmp
Database Links Reactome: R-HSA-1592389
Cellular Localisation Isoform Long: Cell Membrane
Single-Pass Type I Membrane Protein
Extracellular Side
Localized At The Cell Surface Of Melanoma Cells
Isoform Short: Secreted
Extracellular Space
Extracellular Matrix
Cell Surface
Alternative Antibody Names Anti-Matrix Metalloproteinase-16 antibody
Anti-Mmp-16 antibody
Anti-Mmp-X2 antibody
Anti-Membrane-Type Matrix Metalloproteinase 3 antibody
Anti-Mt-Mmp 3 antibody
Anti-Mtmmp3 antibody
Anti-Membrane-Type-3 Matrix Metalloproteinase antibody
Anti-Mt3-Mmp antibody
Anti-Mt3mmp antibody
Anti-MMP16 antibody
Anti-C8orf57 antibody
Anti-MMPX2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance