Anti-MMP11 antibody (389-488) [S6MR] (STJ11101276)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal MMP11 (389-488) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S6MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:4000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MMP11 |
| Gene ID | 4320 |
| Uniprot ID | MMP11_HUMAN |
| Immunogen Region | 389-488 |
| Immunogen Sequence | AALVWGPEKNKIYFFRGRDY WRFHPSTRRVDSPVPRRATD WRGVPSEIDAAFQDADGYAY FLRGRLYWKFDPVKVKALEG FPRLVGPDFFGCAEPANTFL |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 389-488 of human MMP11 (P24347). |
Additional Info
| Tissue Specificity | Specifically expressed in stromal cells of breast carcinomas. |
| Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
| Function | May play an important role in the progression of epithelial malignancies. |
| Protein Name | Stromelysin-3Sl-3St3Matrix Metalloproteinase-11Mmp-11 |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1474228Reactome: R-HSA-1592389 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Stromelysin-3 antibodyAnti-Sl-3 antibodyAnti-St3 antibodyAnti-Matrix Metalloproteinase-11 antibodyAnti-Mmp-11 antibodyAnti-MMP11 antibodyAnti-STMY3 antibody |
Information sourced from Uniprot.org