Anti-MMP11 antibody (389-488) [S6MR] (STJ11101276)

SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ11101276
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General Information

Short DescriptionRabbit monoclonal MMP11 (389-488) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDS6MR
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:1000-1:4000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolMMP11
Gene ID4320
Uniprot IDMMP11_HUMAN
Immunogen Region389-488
Immunogen SequenceAALVWGPEKNKIYFFRGRDY WRFHPSTRRVDSPVPRRATD WRGVPSEIDAAFQDADGYAY FLRGRLYWKFDPVKVKALEG FPRLVGPDFFGCAEPANTFL
SpecificityA synthetic peptide corresponding to a sequence within amino acids 389-488 of human MMP11 (P24347).

Additional Info

Tissue Specificity Specifically expressed in stromal cells of breast carcinomas.
Post Translational Modifications The precursor is cleaved by a furin endopeptidase.
Function May play an important role in the progression of epithelial malignancies.
Protein Name Stromelysin-3
Sl-3
St3
Matrix Metalloproteinase-11
Mmp-11
Database Links Reactome: R-HSA-1442490
Reactome: R-HSA-1474228
Reactome: R-HSA-1592389
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Antibody Names Anti-Stromelysin-3 antibody
Anti-Sl-3 antibody
Anti-St3 antibody
Anti-Matrix Metalloproteinase-11 antibody
Anti-Mmp-11 antibody
Anti-MMP11 antibody
Anti-STMY3 antibody

Information sourced from Uniprot.org

Citations

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